Bestsellers 

    Engineered to reverse skin’s visible biological age1.

    Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

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      HOW OUR TOPICAL PEPTIDE WORKS

      Discover the science behind the OS-01 Peptide™ 

      It's the first peptide proven to reduce cellular senescence, a key driver of aging in the skin and hair.1-3

    WHAT CAUSES AGING?

    A main culprit: cellular senescence 

    With age and exposure to environmental stressors, cells enter a dysfunctional state known as senescence.

    Often called “zombie cells,” senescent cells release inflammatory factors and enzymes that break down tissue and push neighboring healthy cells into premature senescence, triggering a cascade of cellular aging.

    As the body becomes less efficient at clearing them out, their build up leads to:

    Increased Inflammation

    Suppressed Immune Function

    Accelerated aging

    “By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies”–containing the spread of senescence and slowing down skin aging.” 

    – Alessandra Zonari, PhD
OneSkin Co-Founder & Chief Scientific Officer

    THE SOLUTION

    Target skin aging at the source with the OS-01 Peptide™ 

    Built on a decade of longevity science, our proprietary peptide reverses skin's visible biological age by reducing the visible effects of senescent cells.1,4 The result? Healthier, more vibrant skin and hair that not only looks younger, but feels and acts younger over time.5-7

     The real proof? It’s in the numbers. 

    • 10+

      Years of Research

    • 900+

      Peptides Screened

    • 22+

      Patents & Publications

    • 15,000+

      5-Star Reviews

      OUR APPROACH

       Led by science, not hype. 

      Rigorous R&D platform

      End-to-end product development run by our in-house team of scientists.

      Ongoing clinical studies

      Conducted by independent, third-party research organizations.

      Scientifically validated claims

      Quantified by our proprietary MolClock and Skin Age Modeling methods.

      Peer-reviewed publications

      The gold standard for scientific research and in skincare.

       Frequently asked questions 

      What are peptides?

      Peptides are short chains of amino acids. They represent a broad class of molecules with many jobs, from forming the building blocks of larger proteins to acting as cellular messengers. Peptides found naturally in the body (called endogenous peptides), play a crucial role in tissue growth, hormone regulation, and other biological processes. Exogenous peptides, which can be injected, ingested or delivered topically can send out signals to cells to trigger collagen and hyaluronic acid production, aid in cellular repair, and help strengthen the skin barrier. Learn more about what the OS-01 Peptide™ can do here.

      How does the OS-01 Peptide™ work?

      With age and exposure to environmental stressors, some cells enter a dysfunctional state known as senescence. These 'zombie cells' release inflammatory factors that trigger nearby healthy cells to become senescent, leading to accelerated skin aging, loss of collagen, and skin weakening. This leads to visible skin aging: sagging, wrinkles, and crepiness. The OS-01 Peptide™ was engineered to reverse the visible effects of cellular senescence, helping skin look, feel, and act younger and healthier over time.

      Who is OneSkin for?

      OneSkin is for everyone. Whether you’re taking a preventative approach or want your skin’s health and appearance to reflect how you feel on the inside, our scientifically proven products work at the cellular level to keep your skin looking, feeling, and acting younger and healthier as you age.2,3

      What skin concerns does OneSkin address?

      You can learn about the specific benefits of each product here.

      How long does it take to see results?

      Just like aging starts at the cellular level and takes time to manifest visibly, the same is true for reversing it. With daily use, our clinical studies show that results show within 12 weeks, though some people see changes even sooner.